Dillyn Leyds would start at fullback with SP Marais shifting to the left-wing while Sergeal Petersen was set to make his return from injury from the bench.
In their first test match in a summer dominated by the one-day World Cup, England could not even muster three figures against a nation playing its third test match ever.
Australia coach Michael Cheika said the reshuffle was about giving as many players as possible a chance to impress ahead of the World Cup in Japan later this year.
Craig Barry was is stranger to the Cheetahs, as he has previously represented the team in nine Pro14 matches while on a loan-deal from Western Province.
Kristof Milak sliced a whopping 0.78 seconds off Michael Phelps's previous world best, which was achieved during the bodysuit era, after flirting with the record for much of the past season.