Xhaka has had a fractured relationship with the fans since he reacted angrily to being booed when he was substituted against Crystal Palace in October.
They have the joint biggest lead in top-flight history at this stage of the campaign and no team has ever failed to win the title with an advantage of this size.
Vernon Philander took four for 16 in 14.2 overs as South Africa appeared to have taken control by bowling out England for 181, a first innings lead of 103.
The entertainer, whose career has spanned more than five decades, was joined on the prestigious annual achievement list by Oscar-winning Hollywood directors Sam Mendes and Steve McQueen.
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The explosion occurred in a busy area prone to heavy traffic due to a security checkpoint and a taxation office.
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This is in the wake of yet another life lost on Christmas Day at a bogus circumcision school in Crown Mines, in southern Johannesburg.
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At the close on day three, the home team were 137 for four, building on their first innings 467 to be 456 runs in front.
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James Anderson marked his 150th test and return to the England attack with the first-ball wicket of home opener Dean Elgar, and Sam Curran also grabbed a scalp in his first over when Jonny Bairstow caught Aiden Markram for 20.
Harry Kane followed up his own shot to equalise in the 53rd minute and cancel out Adam Webster’s first-half header.
James Anderson marked his 150th cap and return to the England attack at Centurion Park with the first-ball wicket of home opener Dean Elgar, as Sam Curran and Stuart Broad took two scalps each.
